Background-Free 3D Nanometric Localization and Sub-nm Asymmetry Detection of Single Plasmonic Nanoparticles by Four-Wave Mixing Interferometry with Optical Vortices

Abstract

Despite many advances, rapid, precise 3D tracking of nanoscale particles in a complex environment remains challenging. A new technique based on four-wave mixing interferometry not only precisely tracks a gold nanoparticle but also is sensitive to particle asymmetry and orientation.